Product Details
1/EA
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In StockAdditional Information
| Product Name | Ruxience 500 mg/50 mL Vial |
| Application | Treatment of B-cell malignancies and autoimmune disorders |
| Active Ingredient | Rituximab-pvvr |
| Mechanism of Action | CD20-directed cytolytic monoclonal antibody leading to B-cell depletion |
| Dosage Form | Intravenous Injection |
| Strength | 500 mg/50 mL (10 mg/mL) |
| Onset of Action | B-cell depletion observed within weeks |
| Common Side Effects | Infusion reactions, fever, chills, nausea, fatigue |
| Precautions | Monitor for infections, infusion reactions, and hematologic toxicities |
| Packaging | Single-dose vial |
| Uses | Treatment of non-Hodgkin’s lymphoma (NHL), chronic lymphocytic leukemia (CLL), rheumatoid arthritis, granulomatosis with polyangiitis, and microscopic polyangiitis |
Description
Ruxience (Rituximab-pvvr) 500 mg/50 mL vial is a biosimilar monoclonal antibody indicated for the treatment of various B-cell malignancies and autoimmune disorders. It is used in patients with non-Hodgkin’s lymphoma (NHL), chronic lymphocytic leukemia (CLL), rheumatoid arthritis, granulomatosis with polyangiitis, and microscopic polyangiitis.
The active ingredient, rituximab-pvvr, binds to CD20, initiating immune-mediated cytotoxicity, complement-dependent cytotoxicity, and direct apoptosis of malignant and overactive B cells. This mechanism is effective in reducing tumor burden in hematologic malignancies and controlling autoimmune inflammation in diseases such as rheumatoid arthritis.
Ruxience is administered as an intravenous infusion, with dosing regimens tailored to the specific condition being treated. Premedication with corticosteroids, antihistamines, and antipyretics is recommended to reduce the risk of infusion-related reactions. Patients should be monitored for infections, hematologic toxicities, and infusion-related adverse events.
Frequently Asked Questions (FAQs)
The cost of RUXIENCE 500MG 50ML VL EA is $$0.00
RUXIENCE 500MG 50ML VL EA is manufactured by Pfizer.
You can purchase RUXIENCE 500MG 50ML VL EA on our website at https://cobalt.pipelinemedical.com/product/detail/ruxience-500mg-50ml-vl-ea-659470