Product Details
CARBOPLATIN 450 MG/45 ML VIAL
Manufacturer: Pfizer
MFG#: 61703-0339-50
NDC: 61703-0339-50
PID: 665782
1/EA
$ *.**
In StockAdditional Information
| Product Name | Carboplatin 450 mg/45 mL Vial |
| Active Ingredient | Carboplatin |
| Drug Class | Platinum-based Antineoplastic |
| Mechanism of Action | Forms DNA crosslinks, inhibiting DNA replication and transcription |
| Strength | 450 mg per 45 mL |
| Volume | 45 mL |
| Route of Administration | Intravenous infusion |
| Side Effects | Myelosuppression, nausea, vomiting, nephrotoxicity, electrolyte imbalance |
| Precautions | Monitor renal function, blood counts; use with caution in patients with bone marrow suppression |
| Storage | Store at 20°C to 25°C; protect from light; do not freeze |
| Packaging | Single-use glass vial |
| Uses | Treatment of ovarian cancer, lung cancer, and other solid tumors |
Description
Carboplatin 450 mg/45 mL vial is a platinum-based chemotherapy agent used in the treatment of various malignancies. It contains carboplatin, a second-generation platinum compound that interferes with DNA replication and transcription, leading to cell cycle arrest and apoptosis. The drug exerts its cytotoxic effects by forming DNA crosslinks, primarily at the N7 position of guanine.
Carboplatin is indicated for the treatment of advanced ovarian carcinoma, small cell lung cancer, and other solid tumors, either as monotherapy or in combination with other chemotherapeutic agents. It is administered via intravenous infusion, with dosing commonly based on the Calvert formula, which considers renal function to reduce toxicity.
The drug has a more favorable toxicity profile compared to cisplatin, with reduced nephrotoxicity and gastrointestinal side effects. However, it is associated with dose-limiting myelosuppression, particularly thrombocytopenia and neutropenia. Other side effects may include nausea, vomiting, electrolyte imbalances, and peripheral neuropathy.
Frequently Asked Questions (FAQs)
The cost of CARBOPLATIN 450 MG/45 ML VIAL is $$0.00
CARBOPLATIN 450 MG/45 ML VIAL is manufactured by Pfizer.
You can purchase CARBOPLATIN 450 MG/45 ML VIAL on our website at https://cobalt.pipelinemedical.com/product/detail/carboplatin-mf-10mg-ml-45ml-665782