Additional Information

Description

Tobramycin 80 mg/2 mL is an aminoglycoside antibiotic formulation used for the treatment of serious bacterial infections caused by Gram-negative organisms. It is particularly effective against Pseudomonas aeruginosa, Klebsiella species, and certain Enterobacteriaceae. The medication works by irreversibly binding to the 30S ribosomal subunit of bacterial cells, inhibiting protein synthesis and leading to bacterial cell death.

This injectable formulation is supplied in a 2 mL multiple-dose vial, with a concentration of 40 mg/mL. It is administered intramuscularly or intravenously by trained healthcare professionals and is used in conditions such as septicemia, respiratory tract infections, urinary tract infections, and intra-abdominal infections.

Tobramycin is generally well-tolerated but requires careful monitoring to minimize the risk of adverse effects, particularly nephrotoxicity and ototoxicity, which are dose- and duration-dependent. Baseline and periodic renal function tests and audiometric evaluations are recommended during therapy.